Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• Intelligence Education and Research, Hanyang University, Ansan 426-791, South Korea 10.3762/bjnano.13.92 Abstract Biomimetic materials for better bone graft substitutes are a thrust area of research among researchers and clinicians. Autografts, allografts, and synthetic grafts are often utilized to repair and

• tissue engineering applications. Keywords: antibacterial activity; biomimetic materials; bone graft substitutes; chitosan; gold; osteoinductive; silver; Introduction Bone-related defects and diseases are a serious concern to the life of patients [1]. Autografts, allografts, and synthetic grafts are

• properties to bone graft substitutes. Therefore, to get all the three properties of bone graft substitutes, synthetic biomaterials are often mixed with growth factors and host-derived cells to increase bone formation [3]. Bone tissue engineering is the process of developing bone graft biomaterials with the